nicd fragment Search Results


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Genechem nicd cdna fragment (5456 to 7819 nucleotides; nm_001105721(1747-2531aa)
Regulation of Notch1 signaling significantly alters cell proliferation in normal adult rat brain. Immunostaining shows the increasing number of DCX+ cells on day 3 following TBI in <t>NICD-Ad</t> group, compared with sham-TBI ( A–D ) and NC-TBI ( E–H ) groups.
Nicd Cdna Fragment (5456 To 7819 Nucleotides; Nm 001105721(1747 2531aa), supplied by Genechem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Regulation of Notch1 signaling significantly alters cell proliferation in normal adult rat brain. Immunostaining shows the increasing number of DCX+ cells on day 3 following TBI in NICD-Ad group, compared with sham-TBI ( A–D ) and NC-TBI ( E–H ) groups.

Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

Article Title: Notch1 Signaling Activation Contributes to Adult Hippocampal Neurogenesis Following Traumatic Brain Injury

doi: 10.12659/MSM.907160

Figure Lengend Snippet: Regulation of Notch1 signaling significantly alters cell proliferation in normal adult rat brain. Immunostaining shows the increasing number of DCX+ cells on day 3 following TBI in NICD-Ad group, compared with sham-TBI ( A–D ) and NC-TBI ( E–H ) groups.

Article Snippet: We obtained the NICD cDNA fragment (5456 to 7819 nucleotides; NM_001105721(1747-2531aa)) from the cDNA library of Genechem (Shanghai, China).

Techniques: Immunostaining

The alteration of spatial learning and memory in model rats after TBI. ( A ) The cognitive function of the experimental rats decreased significantly after injury. Compared to other groups, the NICD-Ad group recovered more quickly and the escape latency time significantly decreased (P<0.05). ( B ) The diagram represents the memory function through the time that the rats stayed in the target quarter during the probe trial. The results revealed the sham-Ad-TBI group in the target quarter was significantly higher than sham group and NICD-Ad group on day 7 after brain injury and the NICD-Ad group recovered on day 14 after brain injury. ( C ) The diagram also represents the memory function through the time spent searching for the platform in the target quarter. On day 1 after brain injury, the NICD-Ad group had the longest time spent searching in the target quarter. The rats treated with NICD-Ad had the shortest time needed to find the platform on day 3 after brain injury compared to the sham-Ad group rats (P<0.05).

Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

Article Title: Notch1 Signaling Activation Contributes to Adult Hippocampal Neurogenesis Following Traumatic Brain Injury

doi: 10.12659/MSM.907160

Figure Lengend Snippet: The alteration of spatial learning and memory in model rats after TBI. ( A ) The cognitive function of the experimental rats decreased significantly after injury. Compared to other groups, the NICD-Ad group recovered more quickly and the escape latency time significantly decreased (P<0.05). ( B ) The diagram represents the memory function through the time that the rats stayed in the target quarter during the probe trial. The results revealed the sham-Ad-TBI group in the target quarter was significantly higher than sham group and NICD-Ad group on day 7 after brain injury and the NICD-Ad group recovered on day 14 after brain injury. ( C ) The diagram also represents the memory function through the time spent searching for the platform in the target quarter. On day 1 after brain injury, the NICD-Ad group had the longest time spent searching in the target quarter. The rats treated with NICD-Ad had the shortest time needed to find the platform on day 3 after brain injury compared to the sham-Ad group rats (P<0.05).

Article Snippet: We obtained the NICD cDNA fragment (5456 to 7819 nucleotides; NM_001105721(1747-2531aa)) from the cDNA library of Genechem (Shanghai, China).

Techniques: